FNDC5, human/mouse recombinant

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SKU:
7574-10
£135.37
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Description

FNDC5, human/mouse recombinant is available at Gentaur for Next week delivery.

Improves systemic metabolism by increasing energy expenditure.

Biomolecule/Target: FNDC5

Alternates names: Fibronectin Type III Domain-containing Protein 5; Fibronectin Type III Repeat-containing Protein 2

Synonyms: Fibronectin Type III Domain-containing Protein 5; Fibronectin Type III Repeat-containing Protein 2

Background Information: Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.

Reconstitution Instructions: Reconstitute with 100 μl sterile distilled water.

NCBI Gene Symbol: FNDC5

Gene ID: 252995

NCBI Accession: Q8NAU1

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Additional Information

Size:
10 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human/Mouse
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
<0.1 EU/μg by LAL method
Activity (Specifications/test method):
N/A
Biological activity:
N/A
Results:
N/A
Molecular Weight:
~16.0 kDa. (extracellular domain, human (aa 32-152) / mouse (aa 29-149)) is untagged. FNDC5 extracellular domain has 100% identity between human, mouse and rat.
Storage Temperature:
-20°C
Shelf Life:
6 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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