FGF-acidic, Bovine Brain

FGF-acidic, Bovine Brain is available at Gentaur for Next week delivery.

Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration.

Biomolecule/Target:

Alternates names: HBGF-1, ECGF-beta, FIBP, FGFIBP, FIBP-1, ECGF, ECGFA, GLIO703, FGF1, FGF-a, Fibroblast Growth Factor Acidic

Synonyms: HBGF-1, ECGF-beta, FIBP, FGFIBP, FIBP-1, ECGF, ECGFA, GLIO703, FGF1, FGF-a, Fibroblast Growth Factor Acidic

Background Information: Acidic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.

Reconstitution Instructions: Reconstitute the lyophilized aFGF in sterile 50 mM Na2HPO4 pH-7, and 0.5% albumin. The Recommended concentration in cell culture: 1-20 ng/ml.

NCBI Gene Symbol: FGF1

Gene ID: 281160

NCBI Accession: P03968