EZCyp™ Active Human Cytochrome P450 3A4

EZCyp™ Active Human Cytochrome P450 3A4 is available at Gentaur for Next week delivery.

Unique, cost-effective CYP3A4 catalytic system with active recombinant human CYP3A4 coexpressed with the active NADPH reductase in a semipermeable membrane system.

Biomolecule/Target: EZCyp™ Active Human CYP3A4

Alternates names: Cytochrome P450 3A, Cytochrome P450 3A4, Cyt3A4, CYPIIIA, CYPIIIA4, CYP3A, CYP3A4, Microsomal cytochrome P450 3A4, active CYP3A, human cyp3a, human CYP3A4, recombinant human CYP3A4

Synonyms: Cytochrome P450 3A, Cytochrome P450 3A4, Cyt3A4, CYPIIIA, CYPIIIA4, CYP3A, CYP3A4, Microsomal cytochrome P450 3A4, active CYP3A, human cyp3a, human CYP3A4, recombinant human CYP3A4

Background Information: Cytochrome P450 3A4 (CYP3A4, EC 1.14.13.157) is a member of the cytochrome P450 monooxidase (CYP) family of microsomal xenobiotic metabolism enzymes. CYPs are membrane-bound hemeproteins responsible for Phase I biotransformation reactions, in which lipophilic drugs and other xenobiotic compounds are transformed to more hydrophilic products to facilitate excretion from the body. CYP3A4 is expressed in high levels in the liver and intestines, where it catalyzes oxidation of an extraordinarily wide variety of structurally distinct ligands. More than half of all small molecule drugs commonly used by humans are metabolized by CYP3A4. BioVision’s EZCypTM 3A4 is a permeabilized and stabilized dried yeast powder preparation containing recombinant human CYP 3A4 and recombinant human P450 NADPH oxidoreductase co expressed in the same preparation.

Reconstitution Instructions: 100 mM Potassium Phosphate buffer, pH 7.7

NCBI Gene Symbol: CYP3A4

Gene ID: 1576

NCBI Accession: P08684