EZCyp™ Active Human Cytochrome P450 1A2

EZCyp™ Active Human Cytochrome P450 1A2 is available at Gentaur for Next week delivery.

Unique, cost-effective CYP1A2 catalytic system with active recombinant human CYP1A2 coexpressed with the active NADPH reductase in a semipermeable membrane system.

Biomolecule/Target: EZCyp™ Active Human CYP1A2

Alternates names: Cytochrome P450 1A, Cytochrome P450 1A2, Cyt1a2, CYPIA, CYPIA2, Cyp1A2, Microsomal cytochrome P450 1A2, active CYP1A2, human cyp1A2, human CYP1A2, recombinant CYP1A, CP12, P3-450, P450(PA)

Synonyms: Cytochrome P450 1A, Cytochrome P450 1A2, Cyt1a2, CYPIA, CYPIA2, Cyp1A2, Microsomal cytochrome P450 1A2, active CYP1A2, human cyp1A2, human CYP1A2, recombinant CYP1A, CP12, P3-450, P450(PA)

Background Information: Cytochrome P450 1A2 (CYP1A2, EC 1.14.14.1) is a member of the cytochrome P450 monooxidase (CYP) family of microsomal xenobiotic metabolism enzymes. CYPs are membrane-bound hemeproteins responsible for Phase I biotransformation reactions, in which lipophilic drugs and other xenobiotic compounds are converted to more hydrophilic products to facilitate excretion from the body. CYP1A2 metabolizes many antidepressants and antipsychotic drugs, some of its substrates being caffeine, acetaminophen, fluvoxamine and Haloperidol. Expression of CYP1A2 appears to be induced by various dietary constituents like cabbages, cauliflower and broccoli. BioVision’s EZCypTM 1A2 is a permeabilized and stabilized dried yeast powder preparation containing recombinant human CYP1A2 and recombinant human P450 NADPH oxidoreductase co expressed in the same preparation.

Reconstitution Instructions: 100 mM Potassium Phosphate buffer, pH 7.7

NCBI Gene Symbol: CYP1A2

Gene ID: 1544

NCBI Accession: P05177