CXCL10/IP-10/CRG-2, human recombinant

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SKU:
4277-50
£135.37
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Description

CXCL10/IP-10/CRG-2, human recombinant is available at Gentaur for Next week delivery.

Chemoattractant for monocytes, T cells, NK cells, and dendritic cells

Biomolecule/Target: CXCL-10

Alternates names: C-X-C motif chemokine 10 (10 kDa interferon gamma-induced protein) (Gamma-IP10) (IP-10) (Small-inducible cytokine B10) Cleaved into: CXCL10(1-73)

Synonyms: 11 kDa interferon gamma-induced protein, Gamma-IP10, IP-10, Small-inducible cytokine B10

Background Information: Human Chemokine (C-X-C motif) ligand 10(CXCL10),also known as Interferon gamma-inducible protein-10 (IP-10), is a non-ELR chemokine secreted by various cell types including monocytes, endothelial cells and fibroblasts in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemo-attraction for activated T-lymphocytes, inhibition of angiogenesis and antitumor activity.

Reconstitution Instructions: Dissolve in 1x PBS (It is not recommended to reconstitute to a final concentration less than 100 μg/ml). This can further be diluted to other aqueous buffers.

NCBI Gene Symbol: CXCL10

Gene ID: 3627

NCBI Accession: P02778

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
≥95%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg (1 IEU/μg)
Activity (Specifications/test method):
N/A
Biological activity:
The ED50 of rHu CXCL10 as determined by its ability to chemoattract human CXCR3 transfected BaF3 mouse proB cells was 0.02-0.06 μg/mL.
Results:
0.02-0.06 μg/ml
Molecular Weight:
8.8 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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