BioVision Products
CXCL10/IP-10/CRG-2, human recombinant
- SKU:
- 4277-50
Description
CXCL10/IP-10/CRG-2, human recombinant is available at Gentaur for Next week delivery.
Chemoattractant for monocytes, T cells, NK cells, and dendritic cells
Biomolecule/Target: CXCL-10
Alternates names: C-X-C motif chemokine 10 (10 kDa interferon gamma-induced protein) (Gamma-IP10) (IP-10) (Small-inducible cytokine B10) Cleaved into: CXCL10(1-73)
Synonyms: 11 kDa interferon gamma-induced protein, Gamma-IP10, IP-10, Small-inducible cytokine B10
Background Information: Human Chemokine (C-X-C motif) ligand 10(CXCL10),also known as Interferon gamma-inducible protein-10 (IP-10), is a non-ELR chemokine secreted by various cell types including monocytes, endothelial cells and fibroblasts in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemo-attraction for activated T-lymphocytes, inhibition of angiogenesis and antitumor activity.
Reconstitution Instructions: Dissolve in 1x PBS (It is not recommended to reconstitute to a final concentration less than 100 μg/ml). This can further be diluted to other aqueous buffers.
NCBI Gene Symbol: CXCL10
Gene ID: 3627
NCBI Accession: P02778
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
≥95% |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg (1 IEU/μg) |
Activity (Specifications/test method): |
N/A |
Biological activity: |
The ED50 of rHu CXCL10 as determined by its ability to chemoattract human CXCR3 transfected BaF3 mouse proB cells was 0.02-0.06 μg/mL. |
Results: |
0.02-0.06 μg/ml |
Molecular Weight: |
8.8 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |