CTGFL/WISP-2, Human Recombinant

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SKU:
7129-50
€185
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Description

CTGFL/WISP-2, Human Recombinant is available at Gentaur for Next week delivery.

Stimulates mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types

Biomolecule/Target: CTGFL/WISP-2

Alternates names: Connective Tissue Growth Factor-Like protein, CCN5, CT-58

Synonyms: Connective Tissue Growth Factor-Like protein, CCN5, CT-58

Background Information: CTGFL/WISP-2 is a 28.6 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant human CTGFL/WISP-2 is a 24.3 kDa protein of 228 amino acid residues.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not raise to neutral pH. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

NCBI Gene Symbol: CTGFL

Gene ID: 8839

NCBI Accession: O76076

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli.
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
< 0.1 ng/μg of protein (<1EU/μg).
Activity (Specifications/test method):
Determined by its ability to inhibit IGF-II induced proliferation of MCF-7.
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