CIRBP / Cold-inducible RNA-binding protein, human recombinant

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SKU:
7589-20
£135.37
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Description

CIRBP / Cold-inducible RNA-binding protein, human recombinant is available at Gentaur for Next week delivery.

Plays a protective role in the genotoxic stress response

Biomolecule/Target: CIRBP

Alternates names: A18HNRNP, CIRP, CIRBP

Synonyms: A18HNRNP, CIRP, CIRBP

Background Information: CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator. CIRBP can bind the 3'untranslated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for translation. CIRBP affects NF-κB signaling as opposed to IL1B mRNA stability directly.

Reconstitution Instructions: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 mg/ml

NCBI Gene Symbol: CIRBP

Gene ID: 1153

NCBI Accession: Q14011

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Additional Information

Size:
20 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥90%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1.0 EU per μg of the protein as determined by the LAL method.
Activity (Specifications/test method):
N/A
Biological activity:
N/A
Results:
N/A
Molecular Weight:
20.5 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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