CIRBP / Cold-inducible RNA-binding protein, human recombinant

CIRBP / Cold-inducible RNA-binding protein, human recombinant is available at Gentaur for Next week delivery.

Plays a protective role in the genotoxic stress response

Biomolecule/Target: CIRBP

Alternates names: A18HNRNP, CIRP, CIRBP

Synonyms: A18HNRNP, CIRP, CIRBP

Background Information: CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator. CIRBP can bind the 3'untranslated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for translation. CIRBP affects NF-κB signaling as opposed to IL1B mRNA stability directly.

Reconstitution Instructions: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 mg/ml

NCBI Gene Symbol: CIRBP

Gene ID: 1153

NCBI Accession: Q14011