CD46, human recombinant

CD46, human recombinant is available at Gentaur for Next week delivery.

Has cofactor activity for inactivation of complement components C3b and C4b by serum factor I.

Biomolecule/Target: CD46

Alternates names: Membrane cofactor protein isoform 14, AHUS2, MCP, MIC10, TLX, TRA2.10

Synonyms: Membrane cofactor protein isoform 14, AHUS2, MCP, MIC10, TLX, TRA2.10

Background Information: Membrane cofactor protein isoform 14, also known as CD46, is a type I membrane protein that has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is widely distributed on thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm, but not on erythrocyte. Recombinant human CD46 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Reconstitution Instructions: N/A

NCBI Gene Symbol: CD46

Gene ID: 4179

NCBI Accession: P15529