Description
CD46, human recombinant is available at Gentaur for Next week delivery.
Has cofactor activity for inactivation of complement components C3b and C4b by serum factor I.
Biomolecule/Target: CD46
Alternates names: Membrane cofactor protein isoform 14, AHUS2, MCP, MIC10, TLX, TRA2.10
Synonyms: Membrane cofactor protein isoform 14, AHUS2, MCP, MIC10, TLX, TRA2.10
Background Information: Membrane cofactor protein isoform 14, also known as CD46, is a type I membrane protein that has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is widely distributed on thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm, but not on erythrocyte. Recombinant human CD46 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Reconstitution Instructions: N/A
NCBI Gene Symbol: CD46
Gene ID: 4179
NCBI Accession: P15529
Additional Information
Size: |
100 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥85% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per 1 microgram of protein |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
33.8 kDa (302 aa, 35-313 aa + His tag), confirmed by MALDI-TOF. |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
1 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |