Cathepsin K, Active, rat recombinant

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SKU:
7598-50
€185
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Description

Cathepsin K, Active, rat recombinant is available at Gentaur for Next week delivery.

Predominant proteinase responsible for the resorption of the bone matrix.

Biomolecule/Target: Cathepsin K

Alternates names: CTSK, CTSO, CTSO3

Synonyms: CTSK, CTSO, CTSO3

Background Information: Cathepsin K, a member of the papain cysteine proteinase family is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I, collagen type II and osteonectin, thereby playing a role in bone remodeling and resorption in osteoporosis, osteolytic bone metastasis and rheumatoid arthritis (Bromme and Okamoto, 1995; Drake, F. et al 1996; Bossard et al, 1996).

Reconstitution Instructions: N/A

NCBI Gene Symbol: CTSK

Gene ID: 21975

NCBI Accession: O35186

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Rat
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥90%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
The Cathepsin K is fully active as seen from its ability to cleave Cathepsin K-specific fluorescent substrate using the Cathepsin K Activity assay kit (Cat # K141-100).
Biological activity:
The specific activity is >500 mU/mg (1U = 1 µmole/min/mg) as measured by Cathepsin K Activity Assay Kit (Catalog #K141-100)
Results:
The specific activity is >500 mU/mg (1U = 1 µmole/min/mg) as measured by Cathepsin K Activity Assay Kit (Catalog #K141-100)
Molecular Weight:
23.5 kDa (115-329 aa)
Storage Temperature:
-80°C
Shelf Life:
6 months
Concentration:
0.5 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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