BioVision Products
Cathepsin K, Active, rat recombinant
- SKU:
- 7598-50
Description
Cathepsin K, Active, rat recombinant is available at Gentaur for Next week delivery.
Predominant proteinase responsible for the resorption of the bone matrix.
Biomolecule/Target: Cathepsin K
Alternates names: CTSK, CTSO, CTSO3
Synonyms: CTSK, CTSO, CTSO3
Background Information: Cathepsin K, a member of the papain cysteine proteinase family is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I, collagen type II and osteonectin, thereby playing a role in bone remodeling and resorption in osteoporosis, osteolytic bone metastasis and rheumatoid arthritis (Bromme and Okamoto, 1995; Drake, F. et al 1996; Bossard et al, 1996).
Reconstitution Instructions: N/A
NCBI Gene Symbol: CTSK
Gene ID: 21975
NCBI Accession: O35186
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Rat |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
The Cathepsin K is fully active as seen from its ability to cleave Cathepsin K-specific fluorescent substrate using the Cathepsin K Activity assay kit (Cat # K141-100). |
Biological activity: |
The specific activity is >500 mU/mg (1U = 1 µmole/min/mg) as measured by Cathepsin K Activity Assay Kit (Catalog #K141-100) |
Results: |
The specific activity is >500 mU/mg (1U = 1 µmole/min/mg) as measured by Cathepsin K Activity Assay Kit (Catalog #K141-100) |
Molecular Weight: |
23.5 kDa (115-329 aa) |
Storage Temperature: |
-80°C |
Shelf Life: |
6 months |
Concentration: |
0.5 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |
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