c-Jun (1-79)-GST Fusion Protein

c-Jun (1-79)-GST Fusion Protein is available at Gentaur for Next week delivery.

Plays a role in cell proliferation and apoptosis

Biomolecule/Target:

Alternates names: Transcription factor AP-1, (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)

Synonyms: c-Jun

Background Information: c-Jun is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins, and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. The MAP kinase homologue, JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. The activity of JNK is stimulated by the same signals that activates c-Jun.

Reconstitution Instructions: N/A

NCBI Gene Symbol: JUN; AP1; c-Jun

Gene ID: 3725

NCBI Accession: P05412