c-Jun (1-79)-GST Fusion Protein

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SKU:
7001-100
$719.07
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Description

c-Jun (1-79)-GST Fusion Protein is available at Gentaur for Next week delivery.

Plays a role in cell proliferation and apoptosis

Biomolecule/Target:

Alternates names: Transcription factor AP-1, (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)

Synonyms: c-Jun

Background Information: c-Jun is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins, and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. The MAP kinase homologue, JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. The activity of JNK is stimulated by the same signals that activates c-Jun.

Reconstitution Instructions: N/A

NCBI Gene Symbol: JUN; AP1; c-Jun

Gene ID: 3725

NCBI Accession: P05412

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Additional Information

Size:
100 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥90%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
N/A
Activity (Specifications/test method):
C-Jun fusion protein at a concentration of 2 µg/20 µl reaction was phosphorylated in an in vitro kinase assay with 200 µM ATP. After 30 minutes incubation at 30°C, phosphorylation was detected by Western blot with phospho-specific c-Jun antibodies.
Results:
N/A
Molecular Weight:
37.0 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
2 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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