GSK-3a-GST Fusion Protein

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SKU:
7003-100
€185
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Description

GSK-3a-GST Fusion Protein is available at Gentaur for Next week delivery.

A multifunctional protein serine kinase

Biomolecule/Target:

Alternates names: GSK, Glycogen synthase kinase-3 (GSK-3)

Synonyms: GSK

Background Information: GSK-3 is one of the Akt substrates. It can be phosphorylated by Akt at Ser21 of GSK-3α or Ser9 of GSK-3β. The phosphorylation of GSK negatively regulates its kinase activity. The recombinant GSK-3α fusion protein serves as a useful substrate for assaying Akt kinase activity.

Reconstitution Instructions: N/A

NCBI Gene Symbol: GSK3A

Gene ID: 2931

NCBI Accession: P49840

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Additional Information

Size:
100 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
N/A
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
N/A
Activity (Specifications/test method):
GSK-3α fusion protein at a concentration of 2 µg/20 µl reaction was phosphorylated in an in vitro kinase assay with 200 µM ATP. After 30 minutes incubation at 30°C, phosphorylation was detected by Western blot with phospho-specific GSK-3α antibodies.
Results:
N/A
Molecular Weight:
37.0 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
2 mg/ml
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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