BMP-7, human recombinant

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SKU:
4579-50
€185
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Description

BMP-7, human recombinant is available at Gentaur for Next week delivery.

A protein involved in the transformation of mesenchymal cells into bone and cartilage

Biomolecule/Target: BMP-7

Alternates names: Osteogenic Protein 1, BMP-7

Synonyms: Osteogenic Protein 1, BMP-7

Background Information: BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-7 produced from E. coli is a 15.7 kDa monomeric, non-glycosylated, polypeptide chain containing 139 amino acid residues.

Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in H₂O. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

NCBI Gene Symbol: BMP 7

Gene ID: 655

NCBI Accession: P18075

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Additional Information

Size:
50 μg
Adwords:
Yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
BioVision’s recombinant human BMP-7 is biologically active. The ED₅₀ as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 µg/ml.
Results:
2-12 µg/ml
Molecular Weight:
15.7 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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