BMP-12/GDF-7, human recombinant

(No reviews yet) Write a Review
SKU:
4572-20
€185
Frequently bought together:

Description

BMP-12/GDF-7, human recombinant is available at Gentaur for Next week delivery.

A protein with functions in regulating inflammatory and apoptotic pathways

Biomolecule/Target: BMP-12/GDF-7

Alternates names: BMP-12/GDF-7, BMP12/GDF7, BMP 12/GDF 7,

Synonyms: bone morphogenetic protein 12, BMP12, BMP 12

Background Information: BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-12 is highly conserved across species. BMP-12 regulates chondrogenesis, bone morphogenesis, and neuron differentiation. Recombinant human BMP-12 is a 27 kDa disulfide-linked homodimer containing two 122 amino acid polypeptide chains.

Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in H₂O containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers.

NCBI Gene Symbol: BMP12/GDF7

Gene ID: 151449

NCBI Accession: BAD07014

View AllClose

Additional Information

Size:
20 μg
Adwords:
Yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The protein is biologically active as determined by its ability to induce alkaline phosphatase production by ADTC5 mouse chondrogenic cells. The ED₅₀ for this effect is typically 0.2 – 2.5 µg/ml.
Results:
0.2 – 2.5 µg/ml
Molecular Weight:
27 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
View AllClose

0 Reviews

View AllClose