Description
Argininosuccinate Synthetase (ASS1), E. coli, Recombinant is available at Gentaur for Next week delivery.
Involved in urea cycle that catalyzes aspartate, citrulline, and ATP to form argininosuccinate
Biomolecule/Target:
Alternates names: ASSCTLN1, Citrulline--aspartate ligase, argG,, argininosuccinate synthase 1
Synonyms: ASSCTLN1, Citrulline--aspartate ligase, argG,, argininosuccinate synthase 1
Background Information: Argininosuccinate Synthetase is part of the urea cycle. It catalyzes aspartate, citrulline, and ATP to form argininosuccinate. Mutations in the enzyme cause Citrullinemia, preventing the liver from processing nitrogen to urea. Lack of argininosuccinate synthase has also been observed in pancreatic cancer, liver cancer, melanoma
Reconstitution Instructions: Reconstitute the lyophilized protein in H2O with concentration of 1.0 mU/ml. Incubate the reconstituted protein at 25 °C for 15 minutes.
NCBI Gene Symbol: argG
Gene ID: 947590
NCBI Accession: P0A6E4
Additional Information
Size: |
50 mU |
Adwords: |
False |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
E Coli |
Recombinant: |
True |
Source: |
E.coli |
Purity by SDS-PAGE: |
>95% |
Assay: |
SDS-PAGE. |
Activity (Specifications/test method): |
This enzyme has a specific activity of ≥ 500 mU/mg based on its ability to convert citrulline to argininosuccinate, which can be detected fluorometrically at Ex/Em = 535/595 using BioVision’s Methionine Assay Kit (K442). |
Results: |
≥ 500 mU/mg |
Molecular Weight: |
50 kDa with N-terminal 6X-His tag |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Appearance: |
Lyophilized powder |
Handling: |
Centrifuge the vial prior to opening. |