Aprotinin, Active, Bovine Recombinant (AOF)

Aprotinin, Active, Bovine Recombinant (AOF) is available at Gentaur for Next week delivery.

>90% Pure Active, Bovine Recombinant, Animal Origin Free, Aprotinin. Can be used for inhibition of Trypsin and trypsin like enzymes

Biomolecule/Target: Aprotinin

Alternates names: BPTI, Basic protease inhibitor, Pancreatic trypsin inhibitor

Synonyms: BPTI, Basic protease inhibitor, Pancreatic trypsin inhibitor

Background Information: Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. It is present in blood and in most tissues, with a high concentration in lung, inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, Aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins. Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids arranged in a single polypeptide chain, cross-linked by three disulfide bridges. BioVision’s Recombinant Bovine Aprotinin is an animal-origin free protein purified by proprietary chromatographic techniques.

Reconstitution Instructions: Centrifuge the vial prior to opening at low speed. Reconstitute in water to a concentration of 1 mg/ml. The solution can then be diluted into PBS or other aqueous buffers and store at 4°C for 1 week or –20°C for future use. For long-term storage, it is recommended to add a carrier protein (e.g., 0.1% BSA). Avoid repeated freezing and thawing cycles.

NCBI Gene Symbol: BPI

Gene ID: N/A

NCBI Accession: P00974