Aldose Reductase, human recombinant

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SKU:
7361-100
£135.37
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Description

Aldose Reductase, human recombinant is available at Gentaur for Next week delivery.

Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds

Biomolecule/Target: Aldose Reductase

Alternates names: Aldo-keto reductase family1, member B1, AKR1B1, ADR, ALDR1, ALR2, AR

Synonyms: Aldo-keto reductase family1, member B1, AKR1B1, ADR, ALDR1, ALR2, AR

Background Information: Aldose reductase (AKR1B1) is a member of the aldo-keto reductase (AKR) superfamily and catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. This protein is implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Recombinant Aldose reductase (AKR1B) protein was expressed in E.coli and purified by using conventional chromatography techniques.

Reconstitution Instructions: N/A

NCBI Gene Symbol: AKR1B1

Gene ID: 231

NCBI Accession: P15121

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Additional Information

Size:
100 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
Specific activity is approximately 0.2-0.9 units/mg. Enzymatic activity was confirmed by measuring the amount of enzyme catalyzing the oxidation of 1 micromole NADPH/min at 25°C. Specific activity was expressed in units/mg of protein.
Results:
N/A
Molecular Weight:
35.8 kDa (316 aa, 1-316 aa), confirmed by MALDI-TOF.
Storage Temperature:
-80°C
Shelf Life:
12 months
Concentration:
1 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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