BioVision Products
Aldose Reductase, human recombinant
- SKU:
- 7361-100
Description
Aldose Reductase, human recombinant is available at Gentaur for Next week delivery.
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds
Biomolecule/Target: Aldose Reductase
Alternates names: Aldo-keto reductase family1, member B1, AKR1B1, ADR, ALDR1, ALR2, AR
Synonyms: Aldo-keto reductase family1, member B1, AKR1B1, ADR, ALDR1, ALR2, AR
Background Information: Aldose reductase (AKR1B1) is a member of the aldo-keto reductase (AKR) superfamily and catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. This protein is implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Recombinant Aldose reductase (AKR1B) protein was expressed in E.coli and purified by using conventional chromatography techniques.
Reconstitution Instructions: N/A
NCBI Gene Symbol: AKR1B1
Gene ID: 231
NCBI Accession: P15121
Additional Information
Size: |
100 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Specific activity is approximately 0.2-0.9 units/mg. Enzymatic activity was confirmed by measuring the amount of enzyme catalyzing the oxidation of 1 micromole NADPH/min at 25°C. Specific activity was expressed in units/mg of protein. |
Results: |
N/A |
Molecular Weight: |
35.8 kDa (316 aa, 1-316 aa), confirmed by MALDI-TOF. |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
1 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |