Activin B, Human Recombinant

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SKU:
7112-50
$719.07
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Description

Activin B, Human Recombinant is available at Gentaur for Next week delivery.

A TGF-β family member involved in regulation of embryogenesis, osteogenesis, hematopoiesis, reproductive physiology and hormone secretion from the hypothalamic, pituitary and gonadal glands.

Biomolecule/Target: Activin B

Alternates names: Activin beta-B, Inhibin beta-2

Synonyms: Activin beta-B, Inhibin beta-2

Background Information: Activin B is a TGF-β family member that exhibits a wide range of biological activities including regulation of embryogenesis, osteogenesis, hematopoiesis, reproductive physiology and hormone secretion from the hypothalamic, pituitary and gonadal glands. Activin B, like certain other members of the TGF-β family, signals through the ActRII receptor (Activin Receptor type II). Human Activin B is a 25.6 kDa disulfide-linked homodimer consisting of two βB chains, each containing 115 amino acid residues.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in 10 mM Sodium citrate, pH 3.0 to a concentration of 0.5 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

NCBI Gene Symbol: ACVR1B

Gene ID: 91

NCBI Accession: P36896

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
(BTI-Tn-5B1-4) Hi-5 Insect cells
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
< 0.1 ng/μg of protein (<1EU/μg).
Activity (Specifications/test method):
Determined by its ability to inhibit the proliferation of mouse MPC-11 cells.
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