Activin A, human recombinant

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SKU:
4724-1000
€185
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Description

Activin A, human recombinant is available at Gentaur for Next week delivery.

A protein complex enhancing FSH biosynthesis and secretion

Biomolecule/Target:

Alternates names: Inhibin beta-1, FRP, FSH-releasing protein

Synonyms: Inhibin beta-1, FRP, FSH-releasing protein

Background Information: Activin A is a member of the TGFbeta family of proteins produced by many cell types throughout development. Activins interact with Type I and Type II serine/threonine kinases to signal to SMAD proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, metabolism, etc. Activin A is a homodimer of two beta A chains and is not biologically active until the N terminal propeptide is cleaved from each. Human Activin A has 100% amino acid sequence identity to mouse, rat, porcine, bovine and feline proteins. Recombinant human Activin A is a non-glycosylated homodimer, containing two 117 amino acid chains, with a total molecular weight of 26.2 kDa.

Reconstitution Instructions: Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water, which can then be further diluted to other aqueous solutions.

NCBI Gene Symbol: INHBA

Gene ID: 3624

NCBI Accession: P08476

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Additional Information

Size:
1 mg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
≥95%
Assay 2:
HPLC
Endotoxin Level:
<0.1 EU/μg purified protein
Activity (Specifications/test method):
N/A
Biological activity:
The activity is determined by the ability to induce cytoxicity of MPC-11 cells and is typically less than 2 ng/mL.
Results:
< 2 ng/mL
Molecular Weight:
26.2 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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