HDAC1 Immunoprecipitation (IP) & Activity Assay Kit

HDAC1 Immunoprecipitation (IP) & Activity Assay Kitis available at Gentaur for Next week Delivery.

Only kit on the market for both IP and measuring activity of HDAC1.

Description:

Histone deacetylases (HDACs) play a central role in controlling cell cycle regulation, cell differentiation, and tissue development. HDAC1 is ubiquitously expressed and plays a role in cellular senescence, cardiomyocyte differentiation and hypertrophy, aging of the liver, myelination, and adult neurogenesis to name a few functions. The HDAC1 IP & Activity Assay Kit provides an antibody-based method to specifically immunoprecipitate the HDAC1 complex from cells & tissues and to measure HDAC1 activity fluorometrically. HDAC1 is immunoprecipitated from cell, nuclear or tissue extract(s) using HDAC1 antibody followed by capturing the complex on protein-A/G beads. The immunoprecipitated complex is incubated with the HDAC substrate. Only the deacetylated substrate is cleaved by the Developer to produce a fluorophore, which can be easily analyzed using a fluorescence plate reader.

Applications:

Sample Typ:e Human, Mouse or Rat • Cell Lysate and Nuclear Extract • Tissue Extract

Alternate Name: Histone Deacetylase 1 Immunoprecipitation (IP) & Activity Assay Kit

Features and Benefits:

• Simple, fast and convenient. • Only kit on the market for both IP as well as measuring activity of HDAC1