Alpha Galactosidase (α-Gal) Activity Assay Kit (Fluorometric)

Alpha Galactosidase (α-Gal) Activity Assay Kit (Fluorometric)is available at Gentaur for Next week Delivery.

The most sensitive assay to measure α-Gal activity.

Description:

Alpha-Galactosidase (α-Gal; EC 3.2.1.22) hydrolyzes alpha-galactosyl moieties found in glycolipids and glycoproteins. In mammals, α-Gal hydrolyzes poly- and oligosaccharides commonly found in dietary sources that are difficult to digest. Therefore, α-Gal is used in dietary supplements that help to reduce the production of intestinal gases due to consumption of certain foods. It is known total α-Gal activity is due to two major isozymes with unique, yet different thermostability profiles. Alpha-Galactosidase A, is thermolabile and represents approximately 90% of total α-Gal activity. Fabry Disease, a lysosomal disease disorder, is characterized by mutations in alpha-Galactosidase A. These mutations cause abnormal accumulation of glycosphingolipids in lysosomes. BioVision’s Alpha Galactosidase Activity Assay Kit provides a simple, rapid way to monitor total α-Gal activity in wide variety of biological samples. In this kit, α-Gal cleaves a synthetic specific substrate releasing a fluorophore, which can be easily quantified (Ex/Em= 360/445 nm). The assay is specific, sensitive and can detect as low as 0.1 µU of α-Galactosidase activity.

Applications: • Measurement of α-Galactosidase activity in various samples

Sample Typ:e • Animal tissues such as kidney, etc. • Adherent or suspension cells • Biological Fluids: saliva

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Features and Benefits:

• Quick and easy method to measure Alpha Galactosidase activity. • Detection limit: < 0.1 µU. • Specific: does not detect beta galactosidase activity