Lysosomal α-Glucosidase (GAA) Activity Assay Kit (Fluorometric)

(No reviews yet) Write a Review
SKU:
K187-100
€465
Frequently bought together:

Description

Lysosomal α-Glucosidase (GAA) Activity Assay Kit (Fluorometric)is available at Gentaur for Next week Delivery.

Highly Sensitive α-Glucosidase Activity Assay.

Description:

Lysosomal α-Glucosidase (GAA, Acid α-Glucosidase, Acid Maltase; EC 3.2.1.3) is an exo-1,4 and exo-1,6-α-Glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Deficiency in GAA activity results in the accumulation of glycogen within the lysosome, leading to Glycogen storage disease type II [also termed acid maltase deficiency (AMD) or Pompe disease]. Pompe disease is an inherited disorder of glycogen metabolism with broad spectrum of clinical phenotypes. Cardiac and skeletal muscles are the major target tissues and GAA activity in dry blood spots has been used to screen, and diagnose Pompe Disease. BioVision’s Lysosomal α-Glucosidase (GAA) Activity Assay Kit provides a simple way to monitor GAA activity in a wide variety of Biological Samples. In this kit, GAA cleaves a synthetic specific substrate releasing a fluorophore, which can be easily quantified (Ex/Em= 368/460 nm). The assay is specific, sensitive- it can detect as low as 0.05 µU of GAA activity

Applications: · Measurement of Lysosomal α-Glucosidase activity in various tissues/cells.

Sample Typ:e • Tissue Homogenates: Muscle, Heart, etc. • Cell Lysates: 3T3 Cell Lysates, etc. • Biological fluids: Serum, etc.

Alternate Name: α-D-Glucosidase Activity Colorimetric Assay Kit , α-D-Glucoside Glucohydrolase Activity Colorimetric Assay Kit , α-Glucopyranosidase Activity Colorimetric Assay Kit, Maltase Activity Colorimetric Assay Kit, α-1,4-Glucosidase Activity Colorimetric Assay Kit, Glucoinvertase Activity Colorimetric Assay Kit

Features and Benefits:

• Rapid and easy-to-use. • Highly-sensitive & high-throughput capable • This assay kit can measure0.05 µU of α-glucosidase activity in a variety of sample.

View AllClose

Additional Information

Size:
100 assays
Storage Conditions:
4°C-20°C
Shipping Conditions:
gel pack
Shelf life:
12 months
Detection Method:
Fluorescence (368/460 nm)
Category:
α-Glucosidase
View AllClose

0 Reviews

View AllClose