Phospho-ALOX5 (Ser523) Antibody

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SKU:
A1714-100
Availability:
Next week delivery
  • Phospho-ALOX5 (Ser523) Antibody
  • Phospho-ALOX5 (Ser523) Antibody
$1,535.31
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Description

Phospho-ALOX5 (Ser523) Antibodyis available at Gentaur for Next week Delivery.

Description: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

Immunogen Sequence:A synthesized peptide derived from human ALOX5 around the phosphorylation site of Sersine 523.

Target Alternative Name:ALOX5, 5-LOX, Arachidonate 5-lipoxygenase

Species Reactivities:Rat, Human

Tag Line:Polyclonal antibody to detect endogenous levels of Phospho-ALOX5 (Ser523) in human and rat sample

Formulation:In phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification: Affinity purification

Application:Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blotting, ELISA

Positive Control:/

Application And Usages:ELISA (peptide) 1:20000-1:40000, WB 1:500-1:2000, IF/ICC 1:100-1:500

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
100 µl
Antibody Target:
Arachidonate 5-lipoxygenase
Category:
Phospho-specific
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
IgG
Accession Number:
P09917
Gene Id:
240
Concentration:
1 mg/ml
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20°C
Shipping Condition:
Gel Pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
VRAI
Immunocytochemistry Verified:
FAUX
Immunofluorescence Verified:
VRAI
Immunoprecipitation Verified:
FAUX
FACS Verified:
FAUX
ELISA Verified:
VRAI
ChIP Verified:
FAUX
Dot Blot Verified:
FAUX
Flow Cytometry Verified:
FAUX
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