Anti-ALOX5 Antibody

Anti-ALOX5 Antibodyis available at Gentaur for Next week Delivery.

Description: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen Sequence:Recombinant protein of human ALOX5

Target Alternative Name:5 LOX, 5-lipoxygenase, Arachidonate 5 lipoxygenase, arachidonic 5-lipoxygenase delta-10-13 isoform, Leukotriene A4 synthase, mgC163204

Species Reactivities:Rat, Mouse, Human

Tag Line:Polyclonal antibody to detect Anti-ALOX5 Antibody in human, mouse and rat samples.

Formulation:PBS with 0.05% sodium azide, 50% glycerol, PH7.3

Purification: Affinity purification

Application:Immunohistochemistry (IHC), ELISA

Positive Control:/

Application And Usages:IHC 1:50-1:150

Handling:The antibody solution should be gently mixed before use.