ZNF521 Antibody (NT)

ZNF521 Antibody (NT)is available at Gentaur for Next week Delivery.

Description: The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.

Immunogen Sequence:ZNF521 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ZNF521.

Target Alternative Name:Zinc finger protein 521, EHZF, Evi3

Species Reactivities:Human

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Formulation:100 µg (1 mg/ml) in 1X PBS containing 1 mg/ml BSA, 50% glycerol and less than 0.02% sodium azide, pH 7.4.

Purification: Affinity chromatography purified via peptide column

Application:Western blot, ICC, ELISA

Positive Control:Western Blot: HeLa cell Lysate IHC: HeLa cells

Application And Usages:Western Blot: 1 μg/ml, ICC: 2.5 μg/ml, ELISA. However, the optimal conditions should be determined individually.

Handling:The antibody solution should be gently mixed before use.