TrkB Antibody

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SKU:
3593-30T
  • TrkB Antibody
  • TrkB Antibody
£65.12
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Description

TrkB Antibodyis available at Gentaur for Next week Delivery.

Description: Due to the various splice variants, the trk proteins exist as variably glycosylated entities with the major forms having molecular weights of 140-145 kDa, 110 kDa and the unglycosylated form of 80 kDa. trkB contains 33.3% carbohydrate by weight representing modification on 10 of 12 N-glycosylation sites. The primary ligand for trkB is BDNF which induces the phosphorylation of the protein and subsequent binding of PLC-gamma via SH2 domains. TrkB may function to modulate neuronal responses to the neurotrophins acting throμgh trkB such as BDNF.

Immunogen Sequence:Synthetic peptide surrounding amino acid 810 of human TrkB

Target Alternative Name:NTRK2 , GP145-TrkB , TRKB , Trk-B , tyrosine receptor kinase

Species Reactivities:Human, mouse, rat, chicken

Tag Line:/

Formulation:In phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation, Immunofluorescence

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml), immunofluorescence (5-10 µg/ml). However, the optimal concentrations should be determined individually. Trk protein exists as variably glycosylated entities with the major forms having molecular weights of 140 kDa, 110 kDa, and the unglycosylated form of 80 kDa.

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
30 µg
Antibody Target:
TrkB
Category:
TrkB
Lot Number:
50893
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
Q63604
Gene Id:
25054
Concentration:
0.5 mg/ml
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
China
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Not Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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