Phospho-GSK-3a Antibody

Phospho-GSK-3a Antibodyis available at Gentaur for Next week Delivery.

Description: GSK-3 is a serine/threonine protein kinase that phosphorylates and inactivates glycogen synthase. GSK-3 has been implicated in the regulation of cell fate and in the Wnt signaling pathway. GSK-3 plays an important role in the PI3 kinase and Akt mediated cell survival pathways, and its activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3α and Ser9 of GSK-3β.

Immunogen Sequence:Synthetic phospho-peptide derived from human GSK-3a

Target Alternative Name:DKFZp686D0638, GSK-3alpha

Species Reactivities:Human, mouse, rat

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Formulation:100 µg (0.5 mg/ml) affinity-purified rabbit polyclonal phospho-GSK-3a(Ser21/9) polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.

Purification: Affinity purified

Application:Western blot, Immunohistochemistry

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Application And Usages:Western blot analysis (1-2 µg/ml), and Immunohistochemistry (20-30 µg/ml). However, the optimal conditions should be determined individually. The phospho-GSK-3α/β (Ser21/9) antibody detects GSK-3 only when phosphorylated at Ser21 of GSK-3α or Ser9 of GSK-3β.

Handling:The antibody solution should be gently mixed before use.