PEDF Antibody

PEDF Antibodyis available at Gentaur for Next week Delivery.

Description: PEDF is a non-inhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties. PEDF is a 50 kDa glycoprotein created and secreted in many tissues all the way through the body. A key component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells. Additionally, PEDF is capable to inhibit the activity of angiogenic factors such as VEGF and FGF-2. The recognition of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin. The unique range of PEDF activities associate it as a potential therapeutic agent for the treatment of vasculature related neurodegenerative diseases such as age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR).

Immunogen Sequence:Human recombinant PEDF, Cat # 4988

Target Alternative Name:Pigment epithelium-derived factor, PEDF, Serpin-F1, SerpinF1, EPC-1, EPC1, PIG35

Species Reactivities:Human, mouse, rat

Tag Line:Polyclonal Antibody to detect PEDF in human, mouse and rat samples

Formulation:30 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.

Purification: Affinity Purified Antibody

Application:Western blot

Positive Control:Western Blot: Jurkat cell lysate, 3T3 cell lysate, mouse muscle lysate, rat kidney lysate, recombinant protein

Application And Usages:Western blot: 1-4 µg

Handling:The antibody solution should be gently mixed before use.