PEDF, mouse recombinant

(No reviews yet) Write a Review
SKU:
7572-10
€185
Frequently bought together:

Description

PEDF, mouse recombinant is available at Gentaur for Next week delivery.

An angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties

Biomolecule/Target: PEDF

Alternates names: Pigment Epithelium-derived Factor; Stromal Cell-derived Factor 3; Serpin F1; Caspin

Synonyms: Pigment Epithelium-derived Factor; Stromal Cell-derived Factor 3; Serpin F1; Caspin

Background Information: Pigment epithelium-derived factor (PEDF) is a 47 kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.

Reconstitution Instructions: Reconstitute with 100 μl sterile distilled water.

NCBI Gene Symbol: Serpinf1

Gene ID: 20317

NCBI Accession: P97298

View AllClose

Additional Information

Size:
10 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
CHO cells
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
<0.1 EU/μg by LAL method
Activity (Specifications/test method):
N/A
Biological activity:
N/A
Results:
N/A
Molecular Weight:
~47.0 kDa. Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG®-tag.
Storage Temperature:
-20°C
Shelf Life:
6 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
View AllClose

0 Reviews

View AllClose