Nucleostemin/GLN3 Antibody (CT)

Nucleostemin/GLN3 Antibody (CT)is available at Gentaur for Next week Delivery.

Description: Nucleostemin, also designated Nucleolar GTP-binding protein 3, is a member of the MMR1/HSR1 GTP-binding protein family. It is expressed in the nucleoli of adult CNS stem cells, primitive bone marrow cells, and embryonic stem cells and in several cancer cell lines. Nucleostemin is often used as a stem cell marker. Overexpression or depletion of the protein can reduce cell proliferation in CNS stem cells. Nucleostemin shuttles between the nucleus and the nucleolus and may be important in maintaining the proliferative capacity of stem cells. Nucleostemin is important in the growth regulation of liver cancer, gastric cancer and several other cancer types. The gene encoding Nucleostemin is localized to chromosome 3p21.1.

Immunogen Sequence:This Nucleostemin (GNL3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-487 amino acids from the C-terminal region of human Nucleostemin (GNL3).

Target Alternative Name:GNL3; E2IG3; NS; Guanine nucleotide-binding protein-like 3; E2-induced gene 3 protein; Novel nucleolar protein 47; Nucleolar GTP-binding protein 3; Nucleostemin

Species Reactivities:Human.

Tag Line:Polyclonal Antibody to detect Nucleostemin in human samples.

Formulation:This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Application:Western blot, IHC.

Positive Control:Western blot: HL60 cell line lysate, IHC: human hepatocarcinoma tissue.

Application And Usages:WB: 1:1000, IHC: 1:10 – 1:50.

Handling:The antibody solution should be gently mixed before use.