NFkB p50 Antibody

(No reviews yet) Write a Review
SKU:
3354R-30T
  • NFkB p50 Antibody
  • NFkB p50 Antibody
£65.12
Frequently bought together:

Description

NFkB p50 Antibodyis available at Gentaur for Next week Delivery.

Description: Nuclear factor kappa B (NFkB) was identified as a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NFkB is a heterodimer that consists of a 50 kDa DNA binding subunit (p50) and a 65 kDa transactivation subunit (p65/RelA). Both of these subunits exhibit sequence homology to the protooncogene c-Rel. The p50 has an isoform called p49/p52, and both proteins are derived from the amino-terminal of precursor protein p105 and p100. The p50/p65 heterodimer remains in the cytosol in an inactive form as a complex with its inhibitor, IkB. Upon stimulation of cells by a wide variety of stimuli such as lipopolysaccharide (LPS), pro-inflammatory cytokines (IL-1 & TNF, etc.), and viral infection, IkB is phosphorylated and degraded by proteosome. The active NFkB heterodimer is translocated into the nucleus and induces gene expression.

Immunogen Sequence:Synthetic peptide corresponding to the N-terminus of human NFkB p50

Target Alternative Name:NFkBp50, NFkB p50, NF-kBp50, NF-kB p50, NFkappaB p50, NFKB1, NFKB-p105 , NFKB-p50 ,NF-kappa-B ,EBP-1, mgC54151, DKFZp686C01211

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:30 µg (0.5 mg/ml) rabbit anti-NFkB p50 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually.

Handling:The antibody solution should be gently mixed before use.

View AllClose

Additional Information

Size:
30 µg
Antibody Target:
NFkB p50
Category:
NFkB
Lot Number:
51154R
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
BAF84139.1
Gene Id:
4790
Concentration:
0.5 mg/ml
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
China
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Not Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
View AllClose

0 Reviews

View AllClose