LDHAL6B Antibody (NT)

LDHAL6B Antibody (NT)is available at Gentaur for Next week Delivery.

Description: L-Lactate dehydrogenase A chain (LDHA) is a member of the LDH/MDH superfamily and LDH family. It catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is localized primarily in muscle tissue and is part of the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria. LDH1 is decreased in essential thrombocythemia. LDHA is induced through a non-genomic pathway of estrogen action. Reduction in LDH-A activity results in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential. Mutations in LDHA have been associated with in LDHA are the cause of glycogen storage disease type 11 (GSD11) which is a metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.

Immunogen Sequence:This LDHAL6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-71 amino acids from the N-terminal region of human LDHAL6B.

Target Alternative Name:LDHAL6B; LDHAL6; LDHL; L-lactate dehydrogenase A-like 6B

Species Reactivities:Human.

Tag Line:Polyclonal Antibody to detect LDHAL6B in human samples

Formulation:100 µl of antibody in PBS with 0.09% (W/V) sodium azide

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Application:Western blot.

Positive Control:Western blot: K562 cell line lysates

Application And Usages:Western blot: ~1:1000.

Handling:The antibody solution should be gently mixed before use.