HVEM / TNFRSF14 Antibody

HVEM / TNFRSF14 Antibodyis available at Gentaur for Next week Delivery.

Description: TNFRSF14 Antibody: Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-κB and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.

Immunogen Sequence:/

Target Alternative Name:TNFRSF14 Antibody: TR2, ATAR, HVEA, HVEM, CD270, LIGHTR, UNQ329/PRO509, Tumor necrosis factor receptor superfamily member 14, Herpes virus entry mediator A, Herpesvirus entry mediator A, tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)

Species Reactivities:Human and mouse

Tag Line:Rabbit polyclonal unconjugated antibody to detect HVEM/TNFRSF14 in human amd mouse samples

Formulation:/

Purification: /

Application:IHC, WB, IFC

Positive Control:IHC, WB, IFC

Application And Usages:IHC: 1 µg/ml; WB: 1-2 µg/ml; IFC: 10 µg/ml

Handling:The antibody solution should be gently mixed before use