Histone H3 (Citrullinated R2, R8, R17) Antibody

Histone H3 (Citrullinated R2, R8, R17) Antibodyis available at Gentaur for Next week Delivery.

Description: Histone H3 is a nuclear protein that is a component of the histone complex that is essential for the organization of genetic material in eukaryotes. Histone H3 can be citrullinated by protein argine deiminase 4 (PAD4) at positions 2, 8, and 17, which blocks methylation and induces transcriptional repression at target genes. The citrullinated histone H3 is found in neutrophil extracellular traps (NETs), which act to induce production of autoantibodies associated with various diseases such as multiple sclerosis and rheumatoid arthritis.

Immunogen Sequence:Histone H3 peptide citrullinated at R2, R8, and R17

Target Alternative Name:Histone H3; H3 Clustered Histone 1; H3/A; Histone H3.1; Histone H3/A

Species Reactivities:Human

Tag Line:A potential autoimmune disease biomarker

Formulation:TBS, pH 7.4, with 50% glycerol, 0.1% BSA, 0.02% sodium azide

Purification: Peptide affinity purification

Application:ELISA Western Blotting

Positive Control:/

Application And Usages:/

Handling:The antibody solution should be gently mixed before use.