Haptoglobin Polyclonal Antibody

Haptoglobin Polyclonal Antibodyis available at Gentaur for Next week Delivery.

Description: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.

Immunogen Sequence:human Haptoglobin (Cat. No. 7536)

Target Alternative Name:HP, BP, HPA1S, HP2ALPHA2, Zonulin

Species Reactivities:Human, also bind weakly in mouse and rat

Tag Line:Polyclonal Antibody to detect Haptoglobin in Human, Mouse, Rat samples

Formulation:30 µg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin®, and 50 % glycerol.

Purification: Affinity purified rabbit IgG

Application:Western blot

Positive Control:Western blot: h serum, recombinant protein

Application And Usages:Western blot: 1-4 µg/ml

Handling:The antibody solution should be gently mixed before use.