Haptoglobin Polyclonal Antibody

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SKU:
7017-30T
  • Haptoglobin Polyclonal Antibody
  • Haptoglobin Polyclonal Antibody
€89
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Description

Haptoglobin Polyclonal Antibodyis available at Gentaur for Next week Delivery.

Description: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.

Immunogen Sequence:human Haptoglobin (Cat. No. 7536)

Target Alternative Name:HP, BP, HPA1S, HP2ALPHA2, Zonulin

Species Reactivities:Human, also bind weakly in mouse and rat

Tag Line:Polyclonal Antibody to detect Haptoglobin in Human, Mouse, Rat samples

Formulation:30 µg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin®, and 50 % glycerol.

Purification: Affinity purified rabbit IgG

Application:Western blot

Positive Control:Western blot: h serum, recombinant protein

Application And Usages:Western blot: 1-4 µg/ml

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
30 µg
Antibody Target:
Haptoglobin
Category:
Haptoglobin
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
rabbit IgG
Accession Number:
P00738
Gene Id:
3240
Concentration:
0.5 mg/ml
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20°C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Not Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Dot Blot Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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