GSK-3a Antibody

GSK-3a Antibodyis available at Gentaur for Next week Delivery.

Description: Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that has been implicated in the regulation of cell fate and in the Wnt signaling pathway. GSK-3 plays an important role in the PI3 kinase and Akt mediated cell survival pathways, and its activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3α and Ser9 of GSK-3β. GSK-3 has also been implicated in alzheimer’s disease. Six Tau protein isoforms have been identified, all of which are phosphorylated by GSK-3.

Immunogen Sequence:Synthetic peptide from human GSK-3alpha

Target Alternative Name:DKFZp686D0638, GSK-3alpha, Glycogen synthase kinase-3, GSK-3 alpha

Species Reactivities:Human, mouse, rat

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Formulation:100 µg (0.2 mg/ml) affinity-purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.

Purification: Affinity purified

Application:Western blotting, Immunoprecipitation, Immunohistochemistry

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Application And Usages:Western blot analysis (1-2 µg/ml) and Immunohistochemistry (20-30 µg/ml). However, the optimal conditions should be determined individually. The antibody detects GSK-3 from human, mouse, & rat origin; non cross-reactive with GSK-3β.

Handling:The antibody solution should be gently mixed before use.