Description
CRTH2 Polyclonal Antibodyis available at Gentaur for Next week Delivery.
Description: The chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) is a recently identified receptor for the prostaglandin D2 (PGD2) in addition to the classic prostaglandin D receptor. CRTH2 is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, CRTH2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the CRTH2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that CRTH2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo.
Immunogen Sequence:18 amino acid synthetic peptide from near the amino terminus of human CRTH2.
Target Alternative Name:CRTH2 Antibody: DP2, DL1R, CD294, CRTH2, GPR44, Prostaglandin D2 receptor 2, Chemoattractant receptorhomologous molecule expressed on Th2 cells
Species Reactivities:Human, Mouse, Rat
Tag Line:Polyclonal Antibody against AGTR3
Formulation:In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.
Purification: /
Application:WB, IHC, IF
Positive Control:WB, IHC, IF
Application And Usages:WB-1 μg/ml, IHC-P-2.5 μg/ml, IF- 20 μg/ml
Handling:The antibody solution should be gently mixed before use
Additional Information
Size: |
50 µg |
Antibody Target: |
CRTH2 |
Category: |
GPCR |
Host: |
Rabbit |
Antibody Type: |
Polyclonal |
Isotype: |
Rabbit IgG |
Accession Number: |
NP_004769 |
Gene Id: |
11251 |
Concentration: |
0.5 mg/ml |
Appearance: |
Colourless liquid |
Form: |
Liquid |
Storage Condition: |
-20°C |
Shipping Condition: |
gel pack |
Shelf Life: |
12 months |
Country of Animal Origin: |
USA |
Country of Manufacture: |
USA |
Usage: |
For Research Use Only! Not to be used in humans |
Western Blot Verified: |
Verified |
Immunocytochemistry Verified: |
Verified |
Immunofluorescence Verified: |
Verified |
Immunoprecipitation Verified: |
Not Verified |
ELISA Verified: |
Not Verified |
ChIP Verified: |
Not Verified |
Dot Blot Verified: |
Not Verified |
Flow Cytometry Verified: |
Not Verified |