CRTH2 Polyclonal Antibody

CRTH2 Polyclonal Antibodyis available at Gentaur for Next week Delivery.

Description: The chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) is a recently identified receptor for the prostaglandin D2 (PGD2) in addition to the classic prostaglandin D receptor. CRTH2 is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, CRTH2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the CRTH2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that CRTH2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo.

Immunogen Sequence:18 amino acid synthetic peptide from near the amino terminus of human CRTH2.

Target Alternative Name:CRTH2 Antibody: DP2, DL1R, CD294, CRTH2, GPR44, Prostaglandin D2 receptor 2, Chemoattractant receptorhomologous molecule expressed on Th2 cells

Species Reactivities:Human, Mouse, Rat

Tag Line:Polyclonal Antibody against AGTR3

Formulation:In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.

Purification: /

Application:WB, IHC, IF

Positive Control:WB, IHC, IF

Application And Usages:WB-1 μg/ml, IHC-P-2.5 μg/ml, IF- 20 μg/ml

Handling:The antibody solution should be gently mixed before use