Cox-3 Antibody

Cox-3 Antibodyis available at Gentaur for Next week Delivery.

Description: COX proteins are membrane-associated heme proteins that have cyclooxygenase and peroxidase activities. These enzymes are targets of NSAID (Nonsteroidal anti-inflammatory drμgs) such as aspirin. Prostaglandins (PGs) formed by the enzymatic activity of COX-1 are primarily involved in the regulation of homeostatic functions throμghout the body, whereas PGs formed by COX-2 primarily mediate pain, fever, and inflammation. COX-1 is constitutively expressed, with particularly high expression in gastrointestinal tissues. COX-2 is induced by cytokines and mitogens and is likely to play a role in inflammatory diseases such as rheumatoid arthritis. In rodents and humans, COX-3 encodes proteins with completely different amino acid sequences than COX-1 or COX-2 and without COX activity. It has been sμggested COX-3 as the key to unlocking the mystery of the mechanism of action of acetaminophen.

Immunogen Sequence:Synthetic peptide mapping to the N-terminus of mouse Cox-3

Target Alternative Name:PTGS1 , PCOX1 , COX-3 , COX3 , PGHS1 , PGHS-1 , PHS1 , PTGHS

Species Reactivities:Mouse

Tag Line:/

Formulation:30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually.

Handling:The antibody solution should be gently mixed before use.