CD105/Endoglin Antibody (Center E395)

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SKU:
6800-100
$952.28
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Description

CD105/Endoglin Antibody (Center E395)is available at Gentaur for Next week Delivery.

Description: Endoglin (ENG, CD105) is an auxiliary receptor for the TGF-β receptor complex, functioning in related signaling pathways. Endoglin is a transmembrane protein that exists as a disulfide-linked homodimer. It is mainly expressed in vascular and connective tissues and in endothelial and stromal cells. Upregulated endoglin expression has been reported during wound healing and tumor vascularization, and in inflammatory tissues and developing embryos. Mutations in endoglin have been found to be a causal factor of hereditary hemorrhagic telangiectasia (HHT), a disease characterized by malformation of vascular structure. The importance of this protein for normal and tumor vascular function makes it a good marker for endothelial cell proliferation as well as a potential therapeutic target in cancer.

Immunogen Sequence:This CD105 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-409 amino acids from the Central region of human CD105.

Target Alternative Name:ENG; END; Endoglin

Species Reactivities:Human, Mouse.

Tag Line:Polyclonal Antibody to detect CD105 in human and mouse samples.

Formulation:In PBS with 0.09% (W/V) sodium azide.

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Application:Western blot, IHC, FACS.

Positive Control:Western blot: Mouse heart tissue lysate, IHC: mouse heart tissue, FACS: NCI-H292.

Application And Usages:WB: 1:1000, IHC: 1:10 – 1:50, FC: 1:10 – 1:50.

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
100 μl
Antibody Target:
CD105
Category:
CD105
Lot Number:
9G016780
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
P17813
Gene Id:
2022
Concentration:
N/A
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Flow Cytometry Verified:
Verified
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