ApoER2 (LRP8) Antibody (CT)

ApoER2 (LRP8) Antibody (CT)is available at Gentaur for Next week Delivery.

Description: ApoER2 (apolipoprotein E receptor 2), also designated LRP8, is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. ApoER2 is expressed in brain and placenta and has several splice variants. ApoER2 is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

Immunogen Sequence:This APOER2 (LRP8) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 934-963 amino acids from the C-terminal region of human APOER2 (LRP8).

Target Alternative Name:LRP8; APOER2; Low-density lipoprotein receptor-related protein 8; Apolipoprotein E receptor 2

Species Reactivities:Human

Tag Line:Polyclonal Antibody to detect ApoER2 in human samples

Formulation:100 µl of antibody in PBS with 0.09% (W/V) sodium azide

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Application:Western blot, IHC

Positive Control:Western blot: Placenta lysate, IHC: human cancer tissue

Application And Usages:Western blot: ~1:1000, IHC: ~1:50-1:100.

Handling:The antibody solution should be gently mixed before use.