Anti-TIM3 Antibody

Anti-TIM3 Antibodyis available at Gentaur for Next week Delivery.

Description: As a member of the T cell immunoglobulin and mucin domain (TIM) family, Tim-3 is reported to promote or terminate Th1 immunity and is thought to influence a range of inflammatory conditions. It is constitutively expressed in a subset of murine IFNgamma-secreting Th1 cells, but not Th2 cells, in both human and mice. Additionally, Tim-3 is expressed dendritic cells, and by a subset of CD4+ cells where its levels of expression increase upon anti-CD3/28 stimulation. This molecule is also highly expressed in in vitro polarized Th1 cells, and at lower levels in Th17 cells. It is known to synergize with Toll-like receptors and is thought to regulate Th1 and Th17 cytokine secretion.

Immunogen Sequence:KLH-conjugated synthetic peptide of human TIM3

Target Alternative Name:TIM3, TIMD3, Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3

Species Reactivities:Human and Mouse

Tag Line:Polyclonal Antibody to detect TIM3 in human and mouse samples

Formulation:In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide

Purification: Affinity purified

Application:Western blot, IHC

Positive Control:WB: HepG2, BT474, mouse lung, mouse thymus whole cell lysates; IHC: human breast cancer tissue

Application And Usages:WB; 1:500 – 1:1000; IHC: 1:50 – 1:200

Handling:The antibody solution should be gently mixed before use.