Anti-ST2 Detection Antibody

Anti-ST2 Detection Antibodyis available at Gentaur for Next week Delivery.

Description: Suppressor of tumorigenicity (ST2) belongs to the interleukin 1 family of receptors. It exists in two isoforms: soluble form (sST2) found circulating in the plasma and transmembrane receptor form (ST2L). This protein is expressed by cardiomyocytes and vascular endothelial cells. Binding of ST2L to its ligand IL-33, prevents hypertrophy of the myocardium and fibrosis. However, sST2 competes with ST2L to bind to IL-33 and upon binding its ligand, neutralizes the cardioprotective effects of IL-33 and ST2L. Elevated levels of sST2 are associated with ventricular remodeling, fibrosis and chronic heart failure.

Immunogen Sequence:Recombinant ST2

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Species Reactivities:Human

Tag Line:Protein A purified mouse monoclonal antibody to detect ST2 in humans. This antibody is match-paired with Anti-ST2 Capture Antibody (Catalog# A2098) and can be used for applications such as ELISA, Lateral Flow and Chemiluminescence immunoassay (CLIA)

Formulation:In 10 mM PBS, pH 7.4, 0.02% Proclin 300

Purification: Protein A purified

Application:CLIA,Lateral Flow,ELISA

Positive Control:/

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Handling:The antibody solution should be gently mixed before use.