Anti-SARS-CoV-2 S2 Antibody (Clone# AbF712)

Anti-SARS-CoV-2 S2 Antibody (Clone# AbF712)is available at Gentaur for Next week Delivery.

Description: The Spike protein (S) is a type I membrane fusion protein required for viral infection and pathogenesis. It is synthesized as a precursor protein between 1200 to 1300 amino acids. The mature protein is a heavily glycosylated trimer with 21-35 glycosylation sites. Upon cleavage by host proteases, it yields 2 subunits, S1 and S2. The S1 subunit consists of 672 amino acids and is divided into 4 domains: an N-terminal domain, a C-terminal domain (also called receptor binding domain, RBD), and 2 subdomains SD1 and SD2. The S2 subunit consists of 588 amino acids and is divided into 4 domains: an N-terminal hydrophobic fusion peptide (FP), 2 heptad repeats (HR1 and HR2), a transmembrane domain (TM), and a cytoplasmic tail. When S1 recognizes and binds to the host receptor, the S2 subunit undergoes a conformational change to bring about the fusion of viral envelope and host cell membrane. Current strategies involve the development of anti-viral drugs to inhibit infection of coronavirus.

Immunogen Sequence:Recombinant SARS-CoV-2 S2 protein

Target Alternative Name:Spike protein, COVID19, COVID 19, S protein, SARS-CoV S protein, S glycoprotein, E2, Peplomer protein, Spike protein S1, SARS Coronavirus, SARS-CoV-2, SARS CoV 2, 2019-nCoV, Spike protein S2, S2 protein, AbF712

Species Reactivities:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), SARS-CoV

Tag Line:Recombinant monoclonal antibody (Clone# AbF712) to detect the expression of SARS-CoV-2 Spike S2 protein

Formulation:In PBS, pH 7.5

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Handling:The antibody solution should be gently mixed before use.