Anti-Pyruvate Dehydrogenase E2 Polyclonal Antibody

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SKU:
A2336-50
  • Anti-Pyruvate Dehydrogenase E2 Polyclonal Antibody
  • Anti-Pyruvate Dehydrogenase E2 Polyclonal Antibody
€165
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Description

Anti-Pyruvate Dehydrogenase E2 Polyclonal Antibodyis available at Gentaur for Next week Delivery.

Description: The multi-component pyruvate dehydrogenase complex is a group of enzymes in the inner mitochondrial membrane that catalyzes the conversion of pyruvate into acetyl coenzyme A and links glycolysis to the Krebs cycle in cellular respiration. The E2 component, also known as dihydrolipoamide acetyltransferase, accepts the acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to conezyme A. The E2 component is an antigen for antimitochondrial antibodies, which are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis. Disruptions in the E2 gene can cause a deficiency in E2 protein, which can in turn cause primary lactic acidosis in infancy and early childhood.

Immunogen Sequence:Recombinant fusion protein of human pyruvate dehydrogenase E2

Target Alternative Name:Dihydrolipoamide S-Acetyltransferase; PDC-E2; PDCE2; DLTA; PBC; E2; DLAT

Species Reactivities:Mouse Rat Human

Tag Line:Part of the pyruvate dehydrogenase complex that catalyzes the conversion of pyruvate to acetyl CoA

Formulation:In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3

Purification: Affinity purification

Application:Immunofluorescence (IF) Immunohistochemistry (IHC) Western Blotting

Positive Control:/

Application And Usages:/

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
50 µl
Antibody Target:
Human pyruvate dehydrogenase E2
Category:
GM-CSF
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
P10515
Gene Id:
1737
Appearance:
Liquid
Form:
Rabbit IgG
Storage Condition:
-20ºC
Shipping Condition:
Gel Pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
FAUX
Immunocytochemistry Verified:
VRAI
Immunofluorescence Verified:
FAUX
Immunoprecipitation Verified:
VRAI
FACS Verified:
FAUX
ELISA Verified:
FAUX
ChIP Verified:
VRAI
Dot Blot Verified:
FAUX
Flow Cytometry Verified:
FAUX
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